
Necrosis was demonstrated in 43.9% of the lesions in CEUS group and in 6.7% of US group (). The imaging features, number of punctures, diagnostic successful rate, and complication rate between the two groups were compared. The information of CEUS was used for selecting indication and instructing biopsy. The remaining 60 patients only underwent conventional ultrasound (US) before biopsy and were served as US group. Of 142 patients, 82 patients received CEUS before biopsy and were defined as CEUS group. To investigate the value of contrast-enhanced ultrasound (CEUS) in transthoracic biopsy of peripheral lung and mediastinal lesions. LA is a potentially viable minimally invasive treatment that offers good cosmetic effects. Thus, ultrasound-guided LA can effectively inactivate benign thyroid nodules. Three patients had obvious pain during ablation one (1.1%) had recurrent laryngeal nerve injury, but the voice returned to normal within 6 months after treatment. All nodule volumes significantly decreased than that one day after ablation ( P0.05 ). The single-session complete ablation rates for nodules with maximum diameters ≤2 cm, 2-3 cm and ≥3 cm were 93.4%, 70.3% and 61.1%, respectively. Results showed that all benign thyroid nodules successfully underwent LA.


Thyroid nodule volumes, thyroid functions, clinical symptoms and complications were evaluated 1, 3, 6, 12, and 18 months after ablation. Contrast-enhanced ultrasound (CEUS) was used to evaluate complete nodule ablation one day after ablation. LA was performed in 90 patients with 118 benign thyroid nodules. This study aimed to investigate the single-session complete ablation rate of ultrasound-guided percutaneous laser ablation (LA) for benign thyroid nodules. The combination of CEUS guided biopsy and MDT decision-making approach is useful in the diagnostic work-up and therapeutic management. The therapeutic plan was influenced by CEUS guided biopsies findings in the majority of patients (98.3%). CEUS-guided biopsy increased the diagnostic accuracy from 93.3% to 98.3%, with correct diagnosis in 57 of 60 lesions (95.0%). More inner (20.0% versus 6.7%) and surrounding (18.3% versus 2.7%) major vessels were visualized and avoided during biopsies. CEUS enabled the delimitation of more (88.3% versus 41.3%) and larger (14.1 ± 10.7 mm versus 32.3 ± 18.5 mm) nonenhanced necrotic areas. All CEUS findings and clinical data were evaluated in MDT.

Data were recorded and compared with conventional ultrasound (US) guidance group ( n=75 ). CEUS and core needle percutaneous biopsy was performed under real-time CEUS guidance in all lesions. Between Jan 2012 and Dec 2015, 60 consecutive patients (male, 37 female, 23 mean age, 51.3 years ± 14.6) who presented with undetermined abdominal lesions were included. To investigate the value of contrast-enhanced ultrasound (CEUS) guided biopsy of undetermined abdominal lesions in multidisciplinary treatment (MDT) decision-making approach.
